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Sherlock-MS-Blog

Records of the neurodetective  
in the fight against multiple sclerosis


Articles

The Phantom Called PIRA – A Silent Progression🕵️

The Phantom Called PIRA – A Silent Progression🕵️

Multiple Sclerosis is a chameleon of diseases—sometimes loud and dramatic, with relapses and visible lesions. But PIRA is different. No fever, no contrast enhancement. And yet: the patient walks slower, thinks less clearly, lives more restricted.
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The Fluid Escape – A Case Full of Leaks🕵️

The Fluid Escape – A Case Full of Leaks🕵️

We long believed the dura mater — the brain’s outermost membrane — to be merely a protective coat. But the latest evidence? It’s more than that. It’s a distribution hub. Through tiny openings known as ACE points (Arachnoid Cuff Exits), cerebrospinal fluid (CSF) is channeled out like secret passages beneath a Victorian mansion.
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The Silent Power – Astrocytes Under Suspicion🕵️

The Silent Power – Astrocytes Under Suspicion🕵️

They’re rarely mentioned, yet they make up over 30% of all brain cells. Named for their star-shaped appearance, astrocytes were long considered the janitors of the neurons ...
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The Trail of Composite Endpoints 🕵️

The Trail of Composite Endpoints 🕵️

What sounded like a cryptographic cipher turned out to be the latest darling of MS research – a composite biomarker with serious potential.
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The Neuro Detective’s Guide to Motivation

The Neuro Detective’s Guide to Motivation

Today, we embark on a journey through the delightful intricacies of intrinsic motivation—a topic that goes far beyond a mere preference for tea! ☕✨
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The Silent Withdrawal

The Silent Withdrawal

A harmless title? Not at all. Beneath this seemingly simple question lurks – as so often – a complex web of data, risks, immune cells, and a lack of predictive markers. I opened my notebook. The case was on.
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